darbepoetin alfa interactions

Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. List Darbepoetin Alfa-Albumin Solution side effects by likelihood and severity. What should I know regarding pregnancy, nursing and administering Darbepoetin Alfa-Albumin Solution to children or the elderly? Darbepoetin alfa drug interactions (in more detail). Using alcohol or tobacco with certain medicines may also cause interactions to occur.

(1996): 723-4, Swanepoel C, Jacobs P, Byrne MJ, Rayner B, Cassidy MJD, Meyer J "The effect of recombinant human erythropoietin on haematopoiesis in patients undergoing haemodialysis." (1988): 97-100.

Get medical help right away if you have any very serious side effects, including: seizures. Use the medicine exactly as directed. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. BMJ 300 If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911.

Nephron 72 You may need frequent medical tests to be sure this medicine is not causing harmful effects. a light-headed feeling, like you might pass out; shortness of breath (even with mild exertion), swelling, rapid weight gain. If you are injecting this medication under the skin, before each dose, clean the injection site with rubbing alcohol. (1993): 463. Follow all directions on your prescription label and read all medication guides or instruction sheets.

It is recommended to reduce or withhold the use of these agents if blood pressure becomes difficult to control. Some mixtures of medications can lead to serious and even fatal consequences. This effect may be caused by the number of red blood cells increasing too quickly, usually within the first 3 months of starting treatment. It has a 3-fold longer serum half-life compared to epoetin alpha and epoetin beta. Darbepoetin alfa may also be used for purposes not listed in this medication guide. kidney disease (or if you are on dialysis); Tell your doctor if you are pregnant or breastfeeding. Talk with your doctor about the risks and benefits of using this medicine. It works by signaling the bone marrow to make more red blood cells.

(1990): 947-55, Raine AE "Hypertension, blood viscosity, and cardiovascular morbidity in renal failure: implications of erythropoietin therapy."

Before using darbepoetin alfa, tell your doctor or pharmacist if you are allergic to it; or to other drugs that cause more red blood cells to be made (such as epoetin alfa); or if you have any other allergies. Use this medication regularly to get the most benefit from it.

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Follow your doctor's instructions very carefully. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. All rights reserved. Applies to: Seizures, Renal Dysfunction. To help you remember, use it on the same day of the week as directed. (1989): 425-7, Stockenhuber F, Loibl U, Gottsauner-Wolf M, et al "Pharmacokinetics and dose response after intravenous and subcutaneous administration of recombinant erythropoietin in patients on regular haemodialysis treatment or." Otherwise, call a poison control center right away. Erythropoietin interacts with progenitor stem cells to increase red cell production. Do not shake the medicine.

This medication is given as an injection under the skin or into a vein as directed by your doctor. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Avoid combinations; the risk of the interaction outweighs the benefit. Do not freeze darbepoetin alfa, and throw away the medicine if it has become frozen. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This is not a complete list of possible side effects. Aranesp® (darbepoetin alfa) is used to treat a lower than normal number of red blood cells (anemia) caused by chronic kidney disease in patients on dialysis and not on dialysis and anemia caused by chemotherapy that will be used for at least two months after starting Aranesp®.

Are you considering switching to Darbepoetin Alfa-Albumin Solution? (1989): 992-1000, Buckner FS, Eschbach JW, Haley NR, Davidson RC, Adamson JW "Hypertension following erythropoietin therapy in anemic hemodialysis patients." Nephron 59 The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Patients with epilepsy or predisposed to seizures should be monitored closely for blood pressure changes and neurologic symptoms during therapy with these agents. Darbepoetin alfa may cause a serious type of allergic reaction called anaphylaxis. Darbepoetin alfa is given every 1 to 4 weeks, depending on the condition you are treating. Darbepoetin alfa disease interactions. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Ann Intern Med 111 Usual Adult Dose for Anemia Associated with Chemotherapy: Initial dose: 2.25 mcg/kg subcutaneously once a week or 500 mcg subcutaneously once every 3 weeksDuration of therapy: Until completion of chemotherapy courseComments:-Initiate treatment if hemoglobin is less than 10 g/dL and a minimum of 2 additional months of chemotherapy is planned.-Use the lowest dose necessary to avoid RBC transfusions.Use: Treatment of anemia in patients with non-myeloid malignancies where anemia is due to the effect of concomitant myelosuppressive chemotherapy.

Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. (1990): 947-55, Raine AE "Hypertension, blood viscosity, and cardiovascular morbidity in renal failure: implications of erythropoietin therapy." Copyright 1996-2018 Cerner Multum, Inc. Usual Adult Dose for Anemia Associated with Chronic Renal Failure: Chronic Kidney Disease (CKD) Patients Not on Dialysis:Initial dose: 0.45 mcg/kg IV or subcutaneously once every 4 weeks as appropriateComments:-Initiate treatment only when hemoglobin is less than 10 g/dL, rate of hemoglobin decline indicates likelihood of requiring RBC transfusion, and reducing risk of alloimmunization and/or other RBC transfusion-related risks is a goal.CKD Patients on Dialysis:Initial dose: 0.45 mcg/kg IV or subcutaneously once a week or 0.75 mcg/kg once every 2 weeks as appropriateComments:-Initiate treatment when hemoglobin is less than 10 g/dL.-IV route is recommended for patients on hemodialysis. Blood clots (history of) or other problems with the blood or. We would like to show you a description here but the site won’t allow us. Hypertension (high blood pressure), uncontrolled or.

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Appropriate studies have not been performed on the relationship of age to the effects of darbepoetin alfa injection in children with cancer.

Do not dilute or administer in conjunction with other drug solutions. There is 1 alcohol/food interaction with darbepoetin alfa.

Clin Investig 72 WebMD does not provide medical advice, diagnosis or treatment. Moderately clinically significant. Discuss the risks and benefits of darbepoetin alfa with your doctor, as this medication may rarely cause very serious (possibly fatal) side effects, including blood clots, heart attack, stroke, or heart failure.

Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, Bone marrow fibrosis (osteofibrosis cystica) or. There are 18 drug interactions with darbepoetin alfa. Check with your doctor right away if you have a rash, itching, swelling of the face, tongue, and throat, trouble with breathing, or chest pain after you receive the medicine. Results of a phase III multicenter clinical trial." (1989): 992-1000, Buckner FS, Eschbach JW, Haley NR, Davidson RC, Adamson JW "Hypertension following erythropoietin therapy in anemic hemodialysis patients." Darbepoetin alfa side effects (in more detail).

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Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Read and carefully follow any Instructions for Use provided with your medicine. Store in the refrigerator and protect from light.

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