In the probiotic group, the changes in the body weight, body fat percentage, body fat mass and L1 subcutaneous fat area were negatively associated with changes in the levels of C8:1, C14:1, C10 and C12:1 acylcarnitines. Comparative meta-analysis of the effect of, https://doi.org/10.1016/j.micpath.2012.05.007. These authors contributed equally to this work. HT121 increased short chain acids levels in feces. Over a 12-week period, the probiotic group consumed 2 g of probiotic powder, whereas the placebo group consumed the same product without the probiotics. ► Other specific species showed a protective effect against obesity. Conclusions Different Lactobacillus species are associated different effects on weight change that are host-specific. 2020 Jul 29;8(8):1148. doi: 10.3390/microorganisms8081148. Epub 2015 May 14. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Epub 2013 Mar 21. Lactobacillus plantarum was associated with weight loss in animals and Lactobacillus gasseri was associated with weight loss both in obese humans and in animals. Untargeted metabolomics analysis indicated HT121 reversed the levels of discriminant metabolites in liver, such as taurine, isoleucine, L-phenylalanine, methionine, and spermidine changed by HFD. Lactobacillus plantarum was associated with weight loss in animals and Lactobacillus gasseri was associated with weight loss both in obese humans and in animals. Exercise efforts and diet plans to lose weight work better with a healthy and balanced gut microbiome. Copyright © 2020 Elsevier B.V. or its licensors or contributors. In addition, Lactobacillus plantarum is said to sharpen memory, enhance athletic performance, and promote weight loss. ► Specific Lactobacillus species were associated with a weight gain effect. HT121 restored PCOA, major phyla and some genera. Triglyceride-Lowering Effects of Two Probiotics, Lactobacillus plantarum KY1032 and Lactobacillus curvatus HY7601, in a Rat Model of High-Fat Diet-Induced Hypertriglyceridemia.  |  The triglyceride-lowering effect of supplementation with dual probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032: Reduction of fasting plasma lysophosphatidylcholines in nondiabetic and hypertriglyceridemic subjects. Michael DR, Jack AA, Masetti G, Davies TS, Loxley KE, Kerry-Smith J, Plummer JF, Marchesi JR, Mullish BH, McDonald JAK, Hughes TR, Wang D, Garaiova I, Paduchová Z, Muchová J, Good MA, Plummer SF. Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduces fasting triglycerides and enhances apolipoprotein A-V levels in non-diabetic subjects with hypertriglyceridemia. In this study mice received either normal-chow-diet or high–fat-diet (HFD), and drinking water with or without addition of Lactobacillus plantarums HT121 for 11 weeks. HT121 decreased levels of LPS and inflammatory cytokines in serum. Our results provide a new insight in prevention and treatment of obesity and type 2 diabetes. 2020 Jun 8;9(6):1788. doi: 10.3390/jcm9061788. We use cookies to help provide and enhance our service and tailor content and ads. COVID-19 is an emerging, rapidly evolving situation. Different Lactobacillus species are associated different effects on weight change that are host-specific. 2019. Skonieczna-Żydecka K, Kaźmierczak-Siedlecka K, Kaczmarczyk M, Śliwa-Dominiak J, Maciejewska D, Janda K, Stachowska E, Łoniewska B, Malinowski D, Borecki K, Marlicz W, Łoniewski I. J Clin Med. Our previous study showed that supplementation with a combination of Lactobacillus curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 reduced the body weight, body fat percentage, body fat mass and L1 subcutaneous fat area in overweight subjects. 2017 Nov;41(11):1607-1614. doi: 10.1038/ijo.2017.161. Probiotic supplementation significantly increased the levels of octenoylcarnitine (C8:1), tetradecenoylcarnitine (C14:1), decanoylcarnitine (C10) and dodecenoylcarnitine (C12:1) compared with the levels from placebo supplementation. Ahn HY, Kim M, Ahn YT, Sim JH, Choi ID, Lee SH, Lee JH. Also in other studies, probiotic Lactobacillus strains could be tracked in T-RFLP analyses (9, 17, 22). Results were consistent in humans and animals. Lactobacillus Plantarum 299v: The strain Lactobacillu Plantarum 299v is present naturally in our digestive system. Effect of Lactobacillus on body weight and body fat in overweight subjects: a systematic review of randomized controlled clinical trials. 2015 Aug;25(8):724-33. doi: 10.1016/j.numecd.2015.05.002. HT121 decreased the body weight, improved glucose tolerance. Lactobacillus plantarum is another probiotic you should add to your diet to help your weight loss efforts. By continuing you agree to the use of cookies. Proponents often suggest that Lactobacillus plantarum possesses several unique properties that make this probiotic strain especially effective as a health-booster. 2016 Mar;26(3):483-7. doi: 10.4014/jmb.1512.12018. In order to clarify the effect of Lactobacillus-containing probiotics (LCP) on weight we performed a meta-analysis of clinical studies and experimental models. Wiciński M, Gębalski J, Gołębiewski J, Malinowski B. Microorganisms. doi: 10.1371/journal.pone.0059470. USA.gov. Evid Based Complement Alternat Med. Billion Cheers probiotics & prebiotic for weight management, contains essential lactobacillus and Bifidobacterium species to aid weight loss and other associated befits. Sci Rep. 2020 Mar 6;10(1):4183. doi: 10.1038/s41598-020-60991-7. Park DY, Ahn YT, Park SH, Huh CS, Yoo SR, Yu R, Sung MK, McGregor RA, Choi MS. PLoS One. Furthermore, in comparison to the DSS group, ... We investigated the effects of Lactobacillus plantarum on colonic microorganisms in a DSS-induced colitis mouse model. Get the latest research from NIH: https://www.nih.gov/coronavirus. The mice treated with L. plantarum did not lose weight or exhibit a reduced colon length. We primarily attempted to extract and use change from baseline values. We included randomized controlled trials (RCTs) and comparative clinical studies in humans and animals or experimental models assessing the effect of Lactobacillus-containing probiotics on weight. A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements. eCollection 2019. Crovesy L, Ostrowski M, Ferreira DMTP, Rosado EL, Soares-Mota M. Int J Obes (Lond). ELISA analysis showed HT121 decreased levels of LPS and inflammatory cytokines in serum, and increased short chain acids levels in feces. We use cookies to help provide and enhance our service and tailor content and ads. HT121 restored the ratio of Firmicutes/Bacteroidetes. Results were pooled by host and by Lactobacillus species and are summarized in a meta-analysis of standardized difference in means (SMDs). Evid Based Complement Alternat Med. Attention should be drawn to the potential effects of commonly marketed lactobacillus-containing probiotics on weight gain. Epub 2017 Jul 10. 2019 May 9;2019:3291367. doi: 10.1155/2019/3291367. 2019 Apr 15;2019:3862971. doi: 10.1155/2019/3862971. We aimed to evaluate whether the changes in adiposity after supplementation with Lactobacillus strains were associated … 16S rRNA sequencing indicated HT121 restored Firmicutes/Bacteroidetes ratio, PCOA, major phyla, genera of Akkermansia, lactobacillus, and Ruminococcus changed by HFD to the levels of normal group. Further studies are needed to clarify the role of Lactobacillus species in the human energy harvest and weight regulation. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Lactobacilli are reported to reduce weight gain, the mechanism has not been well elucidated.

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